The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 09, 1999

Filed:

Oct. 07, 1994
Applicant:
Inventors:

David E Briles, Birmingham, AL (US);

Janet L Yother, Birmingham, AL (US);

Larry S McDaniel, Birmingham, AL (US);

Assignee:

UAB Research Foundation, Birmingham, AL (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
4242441 ; 4241901 ; 4353201 ; 530350 ; 530825 ;
Abstract

Regions of the PspA protein of the Rx1 strain of Streptococcus pneumoniae have been identified as containing protection-eliciting epitopes which are cross-reactive with PspAs of other S. pneumoniae strains and which is cross-protective. One region comprises the 68-amino acid sequence extending from amino acid residues 192 to 260 of the Rx1 PspA, another region comprises the C-terminal amino acid sequence extending from amino acid residues 293 to 588 of the Rx1 PspA, while a third region comprises the N-terminal amino acid sequence extending from amino acid residues 1 to 115 of the Rx1 PspA.


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