The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 09, 1999
Filed:
Jul. 16, 1998
Applicant:
Inventors:
Hank Kung, Wynnewood, PA (US);
Sanath Meegalla, Drexel Hill, PA (US);
Mei-Ping Kung, Wynnewood, PA (US);
Assignee:
The Trustees of University of Pennsylvania, Philadelphia, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61M / ;
U.S. Cl.
CPC ...
424-165 ; 424-111 ; 424-137 ; 424-91 ; 424-145 ; 534 14 ; 546124 ; 546132 ; 514304 ;
Abstract
This invention presents a series of novel tropane-based derivatives complexed with either technetium or rhenium that are specific for central nervous system receptors, in particular, dopamine or serotonin receptors. The compounds of the invention have utility, inter alia, as imaging agents for CNS receptors. Methods of using these novel compounds as imaging agents are presented, as are intermediates and methods for making these novel compounds