The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 1999

Filed:

Mar. 03, 1998
Applicant:
Inventors:

William H Velander, Blacksburg, VA (US);

Kevin E Van Cott, Shawsville, VA (US);

Roger Van Tassell, Blacksburg, VA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D / ; B01D / ; C02F / ;
U.S. Cl.
CPC ...
536 57 ; 2101982 ; 2105021 ; 210635 ; 210656 ; 96101 ; 502404 ;
Abstract

Relating to chromatographic processes and ion-exchange and affinity matrices, a spatial installation method for a bifunctional reagent that crosslinks and/or activates a polymer matrix is disclosed, with inside-outside installation of a bifunctional reagent on and within a polymer matrix. The polymer matrix is cellulose, agarose, or chitosan particles. The installation may be followed by inside-outside ligand attachment, by further reacting the matrix with a ligand or ionic group so that a higher concentration of ligand or ionic moiety occurs on the intra-particle volume than the outer matrix surface.


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