The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1999
Filed:
Dec. 28, 1995
Applicant:
Inventors:
Malaya Chatterjee, Lexington, KY (US);
Heinz Kohler, Lexington, KY (US);
Sunil K Chatterjee, Lexington, KY (US);
Kenneth A Foon, Lexington, KY (US);
Assignee:
The Board of Trustees of the University of Kentucky, Lexington, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ;
U.S. Cl.
CPC ...
5303872 ; 5303877 ; 5303888 ; 5303897 ; 4241311 ; 4241381 ; 4241551 ; 4241741 ; 435344 ; 435330 ; 435327 ; 435-723 ;
Abstract
The present invention provides a monoclonal anti-idiotype antibody 3H1 that escapes immune tolerance and elicits a specific immune response to CEA in mice, rabbits, monkeys, and patients with advanced CEA-associated disease. This invention also provides compositions which can be used in the detection or treatment of CEA-associated tumors mimics a specific epitope on carcinoembryonic antigen and a hybridoma that produces 3H1.