The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 02, 1999

Filed:

Jul. 31, 1998
Applicant:
Inventors:

Ingo Bonnacker, Nordstemmen, DE;

Hartmut Koehn, Celle, DE;

Gerhard Kristen, Burgdorf, DE;

Christine Reichel, Wedemark, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ;
U.S. Cl.
CPC ...
514284 ; 514397 ; 514962 ; 514960 ; 514970 ; 514973 ; 424451 ; 424452 ; 424464 ; 424465 ; 424489 ;
Abstract

Solid and liquid pharmaceutical preparations containing cilansetron or its acid addition salts as active substance which include an amount sufficient to stabilize cilansetron against racemization, of a physiologically compatible water-soluble acid additive selected from monobasic or multibasic organic acids having 2 to 12 carbon atoms with a first p.sub.s value between 1.1 and 4.8, acid salts of the aforementioned multibasic organic acids, and acid salts of multibasic mineral acids having a first available pK.sub.s value between 1.5 and 7.5, as well as the use of such acid additives for stabilizing cilansetron against racemization in pharmaceutical preparations.


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