The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 02, 1999
Filed:
Sep. 04, 1998
Applicant:
Inventors:
Ronald Craig Rubenstein, Ardmore, PA (US);
Pamela Leslie Zeitlin, Baltimore, MD (US);
Assignee:
Johns Hopkins University, Baltimore, MD (US);
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; G01N / ; G01N / ;
U.S. Cl.
CPC ...
424-91 ; 424-111 ; 424-92 ; 206223 ; 206569 ; 206570 ;
Abstract
The present invention relates to methods of diagnosing CF comprising: stimulating sweat production via .beta.-adrenergic pathway, by increasing cAMP production; collecting sweat into a sweat collection device; determining the sweat rate as a function of the weight of the sweat collected; correlating the sweat rate with the functional state of CFTR and/or presence or absence of CF. The invention also relates to methods of screening compounds for treatment of cystic fibrosis.