The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 26, 1999
Filed:
Oct. 14, 1997
Applicant:
Inventors:
Karen Seibert, St. Louis, MO (US);
Jaime Masferrer, Ballwin, MO (US);
Gary B Gordon, Highland Park, IL (US);
Assignee:
G.D. Searle & Co., Skokie, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N / ; A61K / ;
U.S. Cl.
CPC ...
514406 ; 514210 ; 514247 ; 514252 ; 514341 ; 514365 ; 514372 ; 514374 ; 514378 ; 514399 ; 514400 ; 514403 ; 514407 ; 514602 ; 514603 ; 514604 ; 514605 ; 514709 ;
Abstract
This invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating neoplasia. In particular, the invention describes the method of preventing and treating epithelial cell neoplasia in a subject, said method comprising treating the subject with a therapeutically-effective amount of a compound of Formula I. ##STR1## wherein A, R.sup.2 and R.sup.3 are as described in the specification.