The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 26, 1999

Filed:

Jun. 07, 1995
Applicant:
Inventors:

Joel Haynes, Memphis, TN (US);

Eric A James, Willowdale, CA;

Robert T Garvin, Toronto, CA;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ;
U.S. Cl.
CPC ...
435 697 ; 435 691 ; 435 693 ; 435 711 ; 435 712 ; 435 914 ; 435 9142 ; 43525233 ; 4353201 ; 435471 ; 935 25 ;
Abstract

A novel conjugated protein produced by recombinant DNA techniques comprises a low molecular weight carrier protein portion that is normally self-aggregating to an immunogenic higher molecular weight proteinaceous material and a hapten portion wich is a peptide fraction that contains an epitope for an antigen for a pathogenic disease attached to the low molecular weight carrier portion. On aggregation of the self-aggregating protein, the hapten is on the surface of the viral particle, allowing for recognition of the hapten by the immune system. Upon introduction in vivo, the viral protein produces antibodies to both the self-aggregating protein and the hapten. A plurality of the conjugated proteins having different haptens can be combined into a viral protein to provide multi specific vacicines conferring immunity to a variety of pathogenic agents.


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