The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 19, 1999

Filed:

May. 22, 1998
Applicant:
Inventors:

Mitsunori Ono, Lexington, MA (US);

Keizo Koya, Brookline, MA (US);

Lijun Sun, Decatur, AL (US);

Yumiko Wada, Waltham, MA (US);

Wojciech Wrona, Brookline, MA (US);

Natalie Dales, Arlington, MA (US);

Xueliang Tao, Arlington, MA (US);

Sylvia Holden, Woburn, MA (US);

Assignee:

Shiongi BioResearch Corp., Lexington, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07Z / ; C07Z / ;
U.S. Cl.
CPC ...
544165 ; 5142378 ; 514393 ; 514412 ; 514471 ; 514533 ; 514535 ; 5483027 ; 548516 ; 549496 ; 560 24 ; 560 46 ; 560 47 ;
Abstract

A compound which consists of a proactive alkylating moiety containing an electron-withdrawing group, a bioreductive moiety containing at least two double bonds, and a linker joining the proactive alkylating moiety and the bioreductive moiety.


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