The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 12, 1999
Filed:
Sep. 25, 1997
Applicant:
Inventors:
Lloyd George Czaplewski, Oxford, GB;
Michael George Hunter, Oxford, GB;
Richard Mark Edwards, Oxford, GB;
Keith Martyn Dawson, Oxford, GB;
Assignee:
British Biotech Pharmaceuticals Limited, Oxford, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
530324 ; 530412 ; 435 695 ; 435 711 ; 435 712 ; 435471 ; 435325 ; 4352523 ; 4353201 ;
Abstract
This invention relates to mutants of human RANTES (hRANTES) which, relative to the wild-type molecule, have a reduced tendency to aggregate into large multimeric complexes at physiological ionic strength and pH, and are less pro-inflammatory.