The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 12, 1999

Filed:

Jun. 20, 1996
Applicant:
Inventors:

Nicolas Joseph Fasel, Epalinges, CH;

Theresa Ann Glaser, Uzes, FR;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C12Q / ; C07H / ;
U.S. Cl.
CPC ...
4242691 ; 435-6 ; 4353201 ; 43525233 ; 514 44 ; 536 234 ; 536 235 ;
Abstract

The present invention relates to trypanosomatid histones in substantially isolated form for use as a protective antigen against trypanosomatid infection. These histones may be either isolated from the corresponding parasite or be produced by means of recombinant DNA techniques. For the latter purpose the invention also provides genes encoding histones and derivatives of the genes like other nucleic acids and gene products like peptides and proteins. The invention further provides diagnostic tests, pharmaceutical compositions and vaccines comprising the usual excipients and/or adjuvants and at least one histone, a histone encoding gene or a derivative thereof.


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