The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 05, 1999
Filed:
Aug. 08, 1997
Applicant:
Inventors:
Paul N Devine, Lincroft, NJ (US);
Ulf H Dolling, Westfield, NJ (US);
Lisa F Frey, Somerset, NJ (US);
Richard D Tillyer, Westfield, NJ (US);
David M Tschaen, Holmdel, NJ (US);
Yoshiaki Kato, Okazaki, JP;
Assignees:
Merck & Co., Inc., Rahway, NJ (US);
Banyu Pharmaceutical Co., Ltd., Tokyo, JP;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
546112 ; 549447 ; 560 56 ; 560 80 ; 562451 ;
Abstract
This invention relates to a key intermediate in the synthesis of an endothelin antagonist, the synthesis of this key intermediate and the synthesis of an endothelin antagonist using this intermediate in a stereoselective deoxygenation reaction.