The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 1999
Filed:
Jun. 07, 1995
Applicant:
Inventors:
David Ring, Redwood City, CA (US);
Tian-Xiang Shi, Pinole, CA (US);
Assignee:
Chiron Corporation, Emeryville, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; C12N / ;
U.S. Cl.
CPC ...
5303873 ; 5303877 ; 53038722 ; 53038873 ; 5303887 ; 5303888 ; 5303896 ; 5303897 ; 4241361 ; 4241381 ; 4241441 ; 4241531 ; 4241551 ; 4241731 ; 4241741 ; 435328 ; 435330 ; 435334 ; 4353431 ; 435344 ; 435449 ; 435 711 ;
Abstract
This invention relates generally to the field of immunology, in particular that of antibodies and antibody productions. More specifically, this invention relates to bispecific antibodies, the hybrid hybridomas which produce them, the parent hybridomas, the production and selection of the hybridomas and hybrid hybridomas, and the purification of the bispecific antibodies. Specific examples relate to bispecific monoclonal antibodies which recognize both the human multi-drug resistance antigen, P-glycoprotein and human Fc.gamma. receptor III (hFc.gamma.RIII). These bispecific antibodies are useful in killing cancer cells.