The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 1999

Filed:

Apr. 15, 1997
Applicant:
Inventors:

Donald E Staunton, Kirkland, WA (US);

Brian P Lispky, Seattle, WA (US);

Assignee:

ICOS Corporation, Bothell, WA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435-71 ; 435-72 ; 435325 ; 435 691 ; 530350 ; 530300 ; 536 235 ; 536 231 ;
Abstract

The present invention provides purified and isolated polynucleotides encoding IRP (integrin regulatory protein) polypeptides which regulate .beta..sub.2 and .beta..sub.7 integrins and which are contemplated to participate in integrin signaling and/or recycling pathways. Also provided are methods for identifying modulators of IRP activities and methods for identifying other proteins which interact with IRP polypeptides in signaling pathways. Modulators of IRP interactions are contemplated to be useful, for example, in monitoring and treating inflammatory processes involving leukocytes.


Find Patent Forward Citations

Staunton, Donald. (1999). Cytoplasmic modulators of integrin regulation/signaling (U.S. Patent No. 5958705). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5958705

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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