The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 1999
Filed:
Oct. 02, 1996
Applicant:
Inventors:
Frederik Willem Van Leeuwen, 3063CL Maarssen, NL;
Johannes Peter Burbach, 3981 SB Bunnik, NL;
Franklin G Grosveld, 3065 NH Rotterdam, NL;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C07H / ; G01N / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435 912 ; 536 231 ; 536 235 ; 536 243 ; 536 2433 ; 530350 ; 5303871 ;
Abstract
The invention encompasses methods and reagents for the diagnosis of a disease caused by or associated with a gene having a somatic mutation giving rise to a frameshift mutation. The methods include the steps of providing a body fluid or tissue sample from a patient; and analyzing the sample for the presence of a gene having a frameshift mutation or a protein encoded thereby, wherein the presence of the mutated gene or encoded protein is indicative of the disease.