The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 28, 1999
Filed:
Jun. 06, 1995
Anna Rydeck, Staffanstorp, SE;
Torsten Almen, Falsterbo, SE;
Mikkel Thaning, Tygelsjo, SE;
Sven Andersson, Lomma, SE;
Lars-Goran Wistrand, Lund, SE;
Klaes Golman, Rungsted Kyst, DK;
Nycomed Imaging AS, Oslo, NO;
Abstract
The invention provides iodinated bis phenyl compounds, useful as X-ray contrast agents, of formula I ##STR1## (wherein each C.sub.6 R.sub.5 moeity may be the same or different; each R denotes a hydrogen or iodine atom or a group M, two or three non-adjacent R groups on each C.sub.6 R.sub.5 moiety denoting iodine atoms and one, two or three R groups on each C.sub.6 R.sub.5 moiety denoting M groups; X denotes a group providing a 1, 2 or 3 atom chain linking the two C.sub.6 R.sub.5 groups, preferably where X is or contains in the bridging chain a carbonyloxy group each C.sub.6 R.sub.5 group being a triodophenyl group or a group in which each R is other than hydrogen; and each M is independently a non-ionic hydrophilic moiety, M preferably being a non-ionic hydrophilic moiety comprising a monohydroxy- or polyhydroxy-alkyl group) and isomers, especially stereoisomers and rotamers, thereof.