The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 28, 1999

Filed:

Jun. 26, 1997
Applicant:
Inventors:

J Wallace Parce, Palo Alto, CA (US);

Michael R Knapp, Redwood City, CA (US);

Assignee:

Caliper Technologies Corportion, Mountain View, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N / ; G01N / ;
U.S. Cl.
CPC ...
204451 ; 204601 ; 422 99 ; 422101 ;
Abstract

The present invention provides for techniques for transporting materials using electrokinetic forces through the channels of a microfluidic system. The subject materials are transported in regions of high ionic concentration, next to spacer material regions of high ionic concentration, which are separated by spacer material regions of low ionic concentration. Such arrangements allow the materials to remain localized for the transport transit time to avoid mixing of the materials. Using these techniques, an electropipettor which is compatible with the microfluidic system is created so that materials can be easily introduced into the microfluidic system. The present invention also compensates for electrophoretic bias as materials are transported through the channels of the microfluidic system by splitting a channel into portions with positive and negative surface charges and a third electrode between the two portions, or by diffusion of the electrophoresing materials after transport along a channel.

Published as:
EP0815940A2; WO9800705A1; AU3501297A; EP0815940A3; EP0909385A1; CN1228841A; US5958203A; US5972187A; BR9710052A; US6042709A; TW394843B; US6080295A; NZ333345A; JP2000514184A; AU726987B2; US6287520B1; US2002017464A1; US6482364B2; JP3361530B2; JP2003075407A; US6547942B1; US2003085126A1; EP0909385A4; EP0815940B1; ATE292519T1; DE69732935D1; DE69732935T2; US7001496B2; JP3795823B2; JP2007108181A; CN1329729C; EP0909385B1;

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