The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 1999
Filed:
Dec. 09, 1998
Applicant:
Inventors:
Herbert J Evans, Richmond, VA (US);
R Manjunatha Kini, Singapore, SG;
Assignee:
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K / ; C07K / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
530333 ; 530326 ; 530327 ; 530328 ; 548533 ; 4241851 ; 4242781 ;
Abstract
The present invention relates to method of producing a conformationally-constrained polypeptide that mimics the activity of an immunomodulator peptide, wherein the method comprises: producing the conformationally-constrained polypeptide, wherein the conformationally-constrained polypeptide contains a protein--protein interaction site of said immunomodulator peptide adjacently flanked on both termini by proline residues in a manner distinct from the manner found in the naturally occurring immunomodulator peptide.