The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 1999
Filed:
Dec. 17, 1997
Applicant:
Inventors:
Steven K Davidsen, Libertyville, IL (US);
Douglas H Steinman, Morton Grove, IL (US);
George S Sheppard, Wilmette, IL (US);
Lianhong Xu, Libertyville, IL (US);
James H Holms, Gurnee, IL (US);
Yan Guo, Gurnee, IL (US);
James B Summers, Libertyville, IL (US);
Alan S Florjancic, Lake Bluff, IL (US);
Michael R Michaelides, Gurnee, IL (US);
Assignee:
Abbott Laboratories, Abbott Park, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514183 ; 540453 ; 540454 ; 540455 ; 540456 ; 540457 ; 540458 ; 540459 ; 540460 ; 540461 ; 540463 ;
Abstract
Macrocyclic compounds of formula ##STR1## are potent inhibitors of matrix metalloproteinase and are useful in the treatment of diseases in which matrix metalloproteinase play a role. Also disclosed are matrix metalloproteinase inhibiting compositions and a method of inhibiting matrix metalloproteinase in a mammal.