The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 1999
Filed:
Jul. 11, 1997
Applicant:
Inventors:
Charles E McKenna, Pacific Palisades, CA (US);
Boris A Kashemirov, Venice, CA (US);
Assignee:
University of Southern California, Los Angeles, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07F / ;
U.S. Cl.
CPC ...
558172 ; 560168 ; 562 17 ;
Abstract
.alpha.-(hydroxyimino)phosphonoacetic acids (also referred to as '.alpha.,.alpha.-disubstituted trifunctional oximes' and 'Troika Acids') and their derivatives, and methods to prepare them are disclosed. Also disclosed are the structures and fragmentation pathways of the .alpha.-(hydroxyimino)phosphonoacetic acids. The .alpha.-(hydroxyimino)phosphonoacetic acids and derivatives are useful as pH sensitive chelating agents, enzyme activated drugs, drug delivery agents, phosphorylating reagents and photo-activated reagents.