The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 07, 1999
Filed:
Aug. 04, 1997
Applicant:
Inventors:
Douglas Hurd, Oxford, GB;
Rachel Alison Fallon, Littlemore, GB;
Nicholas Ian Workman, Aylesbury, GB;
Susan Jane Dale, Harrow, GB;
Assignee:
Amersham International PLC, Buckinghamshire, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q / ; C12N / ; C12N / ; C12N / ;
U.S. Cl.
CPC ...
435-6 ; 435-71 ; 435 29 ; 435 697 ; 435 698 ; 435455 ; 435465 ; 435483 ; 536 234 ;
Abstract
The invention relates to modified two-hybrid systems, in particular a reverse two-hybrid system which employs as a reporter a gene encoding a modifying agent such as an enzyme, and a signal agent which is modified by the enzyme usually by being broken down, such that in the event of an inhibition of binding of the two hybrid proteins a detectable signal is produced. The system is particularly useful for drug screening.