The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 31, 1999

Filed:

Jul. 30, 1997
Applicant:
Inventor:

Rina K Dukor, Elmhurst, IL (US);

Assignee:

Vysis, Inc., Downers Grove, IL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
25033911 ; 2503418 ;
Abstract

A method of detecting cellular types in a biological sample supported on an infrared absorptive substrate, such as a plain glass slide, analyzes infrared light reflected from the sample using an Attenuated Total Reflection (ATR) technique. An infrared beam is directed to the sample through an ATR microscope objective. The depth of penetration of the infrared beam in the sample is controlled to avoid infrared spectral response from the absorptive substrate. The attenuated total reflection from the sample is detected and analyzed to determine the cellular types or the presence of anomalies in the sample. The method allows infrared measurements on cell samples mounted on plain glass slides, as are normally used by pathologists and other medical investigators.


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