The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 31, 1999
Filed:
Aug. 05, 1997
Applicant:
Inventor:
Christiane Munkholm, Salem, MA (US);
Assignee:
Bayer Corporation, E. Walpole, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436108 ; 436106 ; 436113 ; 436164 ; 436169 ; 436170 ; 436172 ; 436800 ; 422 55 ; 422 56 ; 422 8205 ; 422 8208 ; 422 8211 ;
Abstract
The present invention provides a urea sensor material having a first layer of a protonated pH sensitive fluorophore immobilized in a hydrophobic polymer, wherein the fluorophore can react quantitatively with ammonia and the transducing moiety of the fluorophore is neutrally charged when deprotonated; a second layer of urease and a polymer; and a third layer of a polymer. The present invention also provides a method for detecting urea using the urea sensor material and optical sensing devices that incorporate the urea sensor material.