The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 1999
Filed:
Aug. 12, 1997
Tetsuro Kuga, Machida, JP;
Satoshi Nakagawa, Machida, JP;
Yoshiyuki Sakaki, Tokyo, JP;
Nanding Zhao, Tokyo, JP;
Hideji Hashida, Tokyo, JP;
Kyowa Hakko Kogyo Co., Ltd., Tokyo, JP;
Abstract
The present invention relates to a DNA selected from DNAs, each having the nucleotide sequence of one of Sequence Nos. 1 to 17, complementary to the RNA strand of mRNA with the varied expression level in patients with Alzheimer's disease, compared with the expression level of the mRNA in normal human brain or a DNA hybridizable with the above-mentioned DNA wherein one or more nucleotides in said DNA are deleted or substituted with other nucleotides or one or more nucleotides are added to said DNA, a polypeptide encoded by the DNA, an antibody recognizing the polypeptide, and the diagnosis, therapeutic treatment and research works of patients with Alzheimer's disease, using the DNA, the polypeptide and the antibody.