The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 10, 1999

Filed:

Jul. 29, 1998
Applicant:
Inventors:

John Duncan Elliott, Wayne, PA (US);

John Gerald Gleason, Downingtown, PA (US);

Jack Dale Leber, Doylestown, PA (US);

Gerald C Simolike, Sharon Hill, PA (US);

Assignee:

SmithKline Beecham Corporation, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N / ;
U.S. Cl.
CPC ...
436 54 ; 436 49 ; 436180 ; 422 63 ; 422 81 ; 422100 ;
Abstract

A mixture of beads from a combinatorial library is held in suspension either by inducing circulating flow of a liquid in a tapered vessel by rising air bubbles or by floating the beads at the interface between two immiscible liquids. Beads are selected individually from the suspension by drawing liquid into the tip of a needle having a circular opening smaller than the diameter of a bead. After a bead is captured on the tip of a needle, excess beads are jarred loose or washed away by flow of a solvent through a sheath surrounding the needle, and the needle is moved by a robotic manipulator to a well into which the bead is released.


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