The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 10, 1999
Filed:
Jan. 02, 1997
Applicant:
Inventors:
Wolfram Eichner, Butzbach, DE;
Volker Achterberg, Hamburg, DE;
Albrecht Dorschner, Hamburg, DE;
Wolfgang Meyer-Ingold, Hamburg, DE;
Heiko Mielke, Neu Wolmstorf, DE;
Wilhem Dirks, Braunschweig, DE;
Manfred Wirth, Wolfenbuttel, DE;
Hansjorg Hauser, Braunschweig, DE;
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; A61K / ;
U.S. Cl.
CPC ...
435 694 ; 435325 ; 435360 ; 4353201 ; 530399 ; 514-2 ; 514 12 ;
Abstract
The recombinant production of PDGF-AB in mammalian cells is disclosed by means of a bicistronic vector system in which an IRES sequence is located between the first and second cistrons and in which the B chain coding gene is located in the first cistron. The disclosed expression unit allows the equilmolar expression of the A and B polypeptide chains.