The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 03, 1999
Filed:
Apr. 11, 1997
Applicant:
Inventors:
Michael Ernest Pierce, Wilmington, DE (US);
Anusuya Choudhury, Landenberg, PA (US);
Rodney Lawrence Parsons, Jr, Wilmington, DE (US);
Lilian Alicia Radesca, Newark, DE (US);
Assignee:
DuPont Pharmaceuticals Company, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ;
U.S. Cl.
CPC ...
544 90 ; 544 71 ; 544 92 ; 549388 ; 564384 ; 564392 ; 564442 ; 564389 ;
Abstract
The present invention provides novel methods for the asymmetric synthesis of (S)-6-chloro-4-cyclopropylethynyl-4-trifluoromethyl-1,4-dihydro-2H-3,1- benzoxazin-2-one of formula (VI-i) ##STR1## which is useful as a human immunodeficiency virus (HIV) reverse transcriptase inhibitor.