The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 03, 1999

Filed:

Dec. 18, 1996
Applicant:
Inventors:

Steven Lee Bender, Oceanside, CA (US);

Chris Allen Broka, Foster City, CA (US);

Jeffrey Allen Campbell, Fremont, CA (US);

Arlindo Lucas Castelhano, New York, NY (US);

Lawrence Emerson Fisher, Mountain View, CA (US);

Robert Than Hendricks, Palo Alto, CA (US);

Keshab Sarma, Sunnyvale, CA (US);

Assignees:

Syntex (U.S.A.) Inc., Palo Alto, CA (US);

Agouron Pharmaceuticals, Inc., San Diego, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N / ; A01N / ; A01N / ; C07C / ; C07C / ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
514317 ; 514319 ; 514327 ; 514330 ; 514331 ; 514354 ; 514357 ; 514423 ; 514438 ; 514451 ; 514565 ; 514588 ; 514595 ; 514618 ; 514625 ; 514628 ; 514825 ; 514885 ; 514900 ; 514903 ; 546192 ; 546195 ; 546225 ; 546227 ; 546229 ; 546233 ; 546235 ; 546238 ; 546239 ; 546242 ; 546245 ; 548531 ; 548537 ; 548566 ; 548572 ; 549 66 ; 549 71 ; 549426 ; 549427 ; 562431 ; 562452 ; 562503 ; 562504 ; 562507 ; 562555 ; 562556 ; 564 42 ; 564 56 ; 564 57 ; 564209 ; 564224 ;
Abstract

The present invention relates to compounds of Formula I: ##STR1## that are matrix metalloprotease inhibitors, pharmaceutical compositions containing them, methods for their use and methods of preparing these compounds.


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