The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 1999
Filed:
Jul. 29, 1997
Alan B Cooper, West Caldwell, NJ (US);
James J-S Wang, Westfield, NJ (US);
Raymond G Lovey, West Caldwell, NJ (US);
Jagdish A Desai, Spotswood, NJ (US);
Anil K Saksena, Upper Montclair, NJ (US);
Viyyoor M Girijavallabhan, Parsippany, NJ (US);
Ronald J Doll, Maplewood, NJ (US);
Schering Corporation, Kenilworth, NJ (US);
Abstract
Novel tricyclic N-cyanoimine compounds and pharmaceutical compositions of formula (1.0) ##STR1## or a pharmaceutically acceptable salt or solvate thereof, wherein a, b, c, d, R.sup.1 -R.sup.8, X and Z are defined herein. Such compounds are inhibitors of the enzyme, farnesyl protein transferase. The compounds are useful for inhibiting Ras function and therefore inhibiting the abnormal growth of cells, in a mammals such as a human.