The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 20, 1999
Filed:
Nov. 03, 1994
Robert P Lenk, The Woodland, TX (US);
Michelle L Tomsho, Levittown, PA (US);
Robert L Suddith, Wilmington, NC (US);
Robert J Klimchak, Flemington, NJ (US);
Andrew S Janoff, Yardley, PA (US);
Sharma R Minchey, Monmouth Junction, NJ (US);
Marc J Ostro, Pennington, NJ (US);
The Liposome Company, Inc., Princeton, NJ (US);
Abstract
This invention provides a multilamellar liposome containing an arachidonic acid metabolite, two or more lipid-containing bilayers and two or more aqueous compartments containing a release-inhibiting buffer. Preferred arachidonic acid metabolites are the prostaglandins, particularly PGE.sub.1. The liposomal formulations can be used to treat animals, particularly humans, for diseases, disorders or conditions which can be ameliorated by prostaglandins, e.g., disorders characterized by cellular activation and adhesion, inflammation and/or toxemia.