The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 1999
Filed:
Jul. 17, 1997
Applicant:
Inventors:
Bernd Peschke, M.ang.l.o slashed.v, DK;
Michael Ankersen, Frederiksberg, DK;
Thomas Kruse Hansen, Herlev, DK;
Henning Tho slashed.gersen, Farum, DK;
Assignee:
Novo Nordisk A/S, Bagsvaerd, DK;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; C07C / ; C07C / ; C07C / ;
U.S. Cl.
CPC ...
514619 ; 514255 ; 514307 ; 514319 ; 514400 ; 514419 ; 514428 ; 514438 ; 514443 ; 544400 ; 546146 ; 546205 ; 5483381 ; 548495 ; 548567 ; 548568 ; 549 58 ; 549 76 ; 564157 ;
Abstract
Novel peptide derivatives, compositions containing them, and their use for treating medical disorders resulting from a deficiency in growth hormone are disclosed. The peptides have the formula (I): ##STR1## wherein a, b, A, R.sup.1, L.sup.1, D, R.sup.3, R.sup.4, R.sup.2, L.sup.2, E and G are as defined in the specification. These peptides exhibit improved resistance to proteolytic degradation, and hence, improved bioavailability.