The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 1999
Filed:
Oct. 07, 1997
Yoshihiko Kanamaru, Tomisato-machi, JP;
Hiroyuki Hirota, Shisui-machi, JP;
Akihiro Shibata, Yachiyo, JP;
Teruo Komoto, Chiba, JP;
Hiroyuki Naito, Narita, JP;
Koichi Tachibana, Narita, JP;
Mari Ohtsuka, Narashino, JP;
Fumio Ishii, Sendai, JP;
Susumu Sato, Narita, JP;
SS Pharmaceutical Co., Ltd., Tokyo, JP;
Abstract
Disclosed herein are substituted benzylurea derivatives represented by the following general formula (1): ##STR1## wherein R.sup.1 and R.sup.2 are independently H, a halogen atom, or an alkyl or alkoxyl group, R.sup.3 is a phenyl or heterocyclic group which may be substituted, n is an integer of 1-6, and R.sup.4 is a phenyl group which may be substituted, or salts thereof, and medicines comprising such a derivative as an active ingredient. The derivatives or salts thereof strongly inhibit only ACAT in macrophages and are hence useful as prophylactic and therapeutic agents for arteriosclerosis.