The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 1999

Filed:

Nov. 13, 1997
Applicant:
Inventors:

Conrad P Dorn, Plainfield, NJ (US);

Jeffrey J Hale, Westfield, NJ (US);

Malcolm Maccoss, Freehold, NJ (US);

Sander G Mills, Woodbridge, NJ (US);

Shrenik K Shah, Metuchen, NJ (US);

Tamara Ladduwahetty, Buckhurst Hill, GB;

Assignee:

Merck & Co., Inc., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; C07D / ; C07D / ; C07D / ; A61K / ; A61K / ;
U.S. Cl.
CPC ...
5142275 ; 5142278 ; 5142282 ; 5142312 ; 5142315 ; 5142335 ; 5142338 ; 5142352 ; 5142358 ; 5142362 ; 5142365 ; 5142368 ; 5142372 ; 544 59 ; 544 60 ; 544 62 ; 544 581 ; 544 584 ; 544106 ; 544111 ; 544114 ; 544122 ; 544128 ; 544129 ; 544132 ; 544133 ; 544137 ; 544139 ; 544140 ; 544141 ; 544143 ; 544145 ; 544146 ; 544148 ; 544152 ; 544153 ;
Abstract

Substituted heterocycles of the general structural formula: ##STR1## are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, asthma and emesis, and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.


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