The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 13, 1999

Filed:

Sep. 29, 1997
Applicant:
Inventors:

Vidyanatha A Prasad, Leawood, KS (US);

Klaus Jelich, Overland Park, KS (US);

Christopher M Tusa, Kansas City, MO (US);

Daniel E Terry, Liberty, MO (US);

Stephen C Slahck, Blue Springs, MO (US);

Scott P Hensley, Kansas City, MO (US);

Assignee:

Bayer Corporation, Pittsburgh, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
B05D / ; A61K / ; C07F / ;
U.S. Cl.
CPC ...
427220 ; 427212 ; 514129 ; 558135 ;
Abstract

The present invention relates to an integrated process for synthesizing dimethyl (2,2,2-trichloro-1-hydroxyethyl)-phosphonate and a process for impregnating the dimethyl (2,2,2-trichloro-1-hydroxyethyl)-phosphonate on to inert carrier granules. The process involves adding dimethyl phosphite to a reaction mixture containing chloral under anhydrous, inert conditions. The molar ratio of chloral to dimethyl phosphite used in the reaction mixture is from about 1.0:1.0 to about 1.1:1.0. The impregnation process involves transferring molten dimethyl (2,2,2-trichloro-1-hydroxyethyl)-phosphonate into a process vessel and discharging weighed aliquots into a formulation vessel to form a granular product containing dimethyl (2,2,2-trichloro-1-hydroxyethyl)-phosphonate.


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