The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 1999

Filed:

Oct. 02, 1998
Applicant:
Inventors:

Michael J Homann, Clinton, NJ (US);

William Brian Morgan, Chatham, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C12P / ;
U.S. Cl.
CPC ...
435121 ; 435170 ; 435171 ; 435197 ; 435280 ; 435822 ; 435872 ; 435874 ; 435886 ; 435911 ; 435913 ; 435917 ; 435921 ; 435931 ; 435933 ;
Abstract

A process for the microbiological or enzymatic hydrolytic resolution of racemic trans-2-(alkoxycarbonylethyl) lactams of the formula I: ##STR1## wherein R is C.sub.1 -C.sub.7 alkyl, 2,2,2-trifluoroethyl or methoxyethoxyethyl and R.sup.1 is hydrogen or a protecting group is disclosed, whereby an optically enriched compound of the formula Ib or IIa: ##STR2## is obtained.


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