The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 1999

Filed:

Oct. 16, 1995
Applicant:
Inventors:

William D Thomas, Jr, Winchester, MA (US);

Thomas P Monath, Harvard, MA (US);

Zhenxi Zhang, Cambridge, MA (US);

Francisco Javier Torres-Lopez, San Clemente, MX;

Wende Lei, Cambridge, MA (US);

David M Lyerly, Radford, VA (US);

James S Moncrief, Christiansburg, VA (US);

Assignee:

OraVax, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ;
U.S. Cl.
CPC ...
4242391 ; 424 946 ; 4242781 ; 4241841 ; 4241921 ; 4242361 ; 4242471 ; 4242341 ; 530300 ; 530350 ; 530825 ; 514-2 ;
Abstract

The invention features methods and compositions for inducing protective and/or therapeutic immune responses to an antigen in a mammal. In these methods, an antigen is administered to the mammal with a toxin of a Clostridium (e.g., C. difficile), or a fragment or derivative thereof having adjuvant activity.


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