The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 06, 1999

Filed:

Mar. 20, 1997
Applicant:
Inventors:

Richard B Greenwald, Somerset, NJ (US);

Anthony J Martinez, Hamilton Square, NJ (US);

Assignee:

Enzon, Inc., Piscataway, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
4241781 ; 4241791 ; 4241941 ; 42419511 ; 4241931 ; 514449 ; 560182 ; 549433 ; 549510 ; 525 541 ; 525 5411 ; 525403 ; 525408 ; 530403 ; 530406 ; 530408 ; 530410 ;
Abstract

Branched, substantially non-antigenic polymers are disclosed. Conjugates prepared with the polymers and biologically active molecules such as proteins and peptides demonstrate extended circulating life in vivo. Substantially fewer sites on the biologically active material are used as attachment sites. Methods of forming the polymer, conjugating the polymers with biologically active moieties and methods of using the conjugates are also disclosed.


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