The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 29, 1999
Filed:
Mar. 14, 1997
Applicant:
Inventors:
Charles F McTiernan, West View, PA (US);
Arthur M Feldman, Fox Chapel, PA (US);
Toru Kubota, Pittsburgh, PA (US);
Carole Frye, Pittsburgh, PA (US);
Assignee:
University of Pittsburgh, Pittsburgh, PA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N / ; G01N / ;
U.S. Cl.
CPC ...
800 18 ; 800-3 ; 800-8 ; 800-9 ; 800 13 ; 800 14 ;
Abstract
The present invention provides transgenic nonhuman mammals that exhibit elevated levels of tumor necrosis factor alpha in myocardium relative to nontransgenic control mammals, and methods for making transgenic non-human mammals. The invention further provides a method for identifying agents useful in the treatment and prevention of cardiac dysfunction.