The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 29, 1999

Filed:

Jun. 08, 1994
Applicant:
Inventors:

R John Collier, Wellesley Hills, MA (US);

Wei Hai Shen, Boston, MA (US);

David Eisenberg, Los Angeles, CA (US);

Seunghyon Choe, Solana Beach, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K / ; A61K / ; A61K / ; C12P / ;
U.S. Cl.
CPC ...
530350 ; 4241831 ; 4241841 ; 4241851 ; 4242031 ; 4242361 ; 4242451 ; 4242391 ; 435 691 ; 435 697 ; 435 29 ;
Abstract

Diphtheria toxin polypeptides comprising a mutant R binding domain exhibit reduced target cell binding and may be used as vaccines to immunize a mammal against infection by Corynebacterium diphtheria.


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