The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 22, 1999
Filed:
Apr. 04, 1997
Applicant:
Inventors:
C Frank Bennett, Carlsbad, CA (US);
Allan Lipton, Hershey, PA (US);
Lois M Witters, York Haven, PA (US);
Assignees:
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
The Penn State Research Foundation, University Park, PA (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H / ; A61K / ;
U.S. Cl.
CPC ...
435375 ; 435-6 ; 514 44 ; 536 231 ; 536 232 ; 536 241 ; 536 245 ;
Abstract
Compounds, compositions and methods are provided for inhibiting the expression of human EGFR. The compositions comprise oligonucleotides complementary to mRNA targeted to nucleic acids encoding EGFR. Methods of using these oligonucleotides for inhibition of EGFR expression and for treatment of diseases such as cancers associated with overexpression of EGFR are provided.