The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 1999
Filed:
Dec. 28, 1995
Applicant:
Inventors:
Claude P Selitrennikoff, Evergreen, CO (US);
Carol S Enderlin, Denver, CO (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ; C12N / ; C12P / ;
U.S. Cl.
CPC ...
435193 ; 435 911 ; 435 9141 ; 4352523 ; 4353201 ; 435325 ; 536 232 ;
Abstract
A (1,3).beta.-glucan synthase mutant useful in the research and development of anti-fungal drugs. A key step in fungal wall assembly, hyphal growth and infection is the synthesis of (1,3).beta.-linked glucan. Because .beta.-glucan is not made by humans, (1,3).beta.-glucan synthase is an attractive target for development of new antifungal antibiotics. A (1,3).beta.-glucan synthase gene has been cloned and the cDNA sequence and polypeptide amino acid sequence of the gene has been established.