The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 1999
Filed:
Sep. 19, 1996
Applicant:
Inventor:
Faye Eggerding, San Francisco, CA (US);
Assignee:
Perkin-Elmer Corporation Applied Biosystems, Foster City, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P / ; C07H / ; C07H / ; C12N / ;
U.S. Cl.
CPC ...
435 912 ; 435-6 ; 435 911 ; 435810 ; 436 231 ; 436 243 ; 436 2433 ; 436 253 ; 935-8 ; 935 76 ; 935 77 ;
Abstract
A method based on polymerase chain reaction (PCR) amplification and oligonucleotide ligase assay (OLA) reaction is provided for analyzing complex genetic systems in a single reaction vessel. The method involves simultaneously incubating a sample containing one or more target polynucleotides with PCR primers and OLA probes in a single reaction mixture. The presence of variant polynucleotide sequences in the sample is determined by detecting and identifying the products of the OLA reaction.
Published as:
CA2195562A1; WO9606190A2; AU3332295A; WO9606190A3; EP0777749A2; JPH09511653A; AU699676B2; US5912148A; US6130073A; JP3102800B2; EP0777749B1; ATE226983T1; DE69528706D1; DE69528706T2;