The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 15, 1999
Filed:
Jun. 16, 1997
Michael Horstmann, Neuwied, DE;
Sylvia Hahn, Bendorf, DE;
Reinhold Meconi, Neuwied, DE;
Robert-Pieter Klein, Neuwied, DE;
LTS Lohmann Therapie-Systeme GmbH, Neuwied, DE;
Abstract
The invention concerns a transdermal therapeutic system comprising the active substance 17-.beta.-estradiol and optionally further active substances, with a laminated structure comprising a backing layer which is substantially impermeable to moisture and impermeable to active substance, one or more matrix layers and, where non-adhesive matrix layers are present, an adhesive layer, characterized in that the concentration of the dissolved estradiol in all matrix layers and, where an adhesive layer is present, in the adhesive layer lies between its saturation concentration in dry condition und its saturation concentration in moist condition, whereby the term 'dry condition' is understood to mean that the base material is in equilibrium with a gas phase with less than 10% relative humidity and the term 'moist condition' is understood to mean that the base material is in equilibrium with a gas phase with more than 90% relative humidity.