The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 18, 1999

Filed:

Apr. 08, 1997
Applicant:
Inventors:

Rajeshwar Singh, Edmonton, CA;

Nian E Zhou, Edmonton, CA;

Degi Guo, Phoenixville, PA (US);

Alan Cameron, Montreal, CA;

Jadwiga Kaleta, Edmonton, CA;

Enrico Purisima, Pierrefonds, CA;

Robert Menard, St. -Laurent, CA;

Ronald George Micetich, Sher Pk., CA;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ;
U.S. Cl.
CPC ...
514210 ; 540347 ;
Abstract

Novel 6-substituted amino-4-oxa-1-azabicyclo�3,2,0!heptan-7-one compounds, as well as the pharmaceutically acceptable salts thereof and diastereoisomers thereof, of formula I, ##STR1## are disclosed, which exhibit excellent cysteine protease inhibitory activity and may be used for treatment of different diseases such as muscular dystrophy, arthritis, myocardial infarction, Alzheimer's disease, bacterial infection, common cold, osteroporosis and cancer metastasis.


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