The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 18, 1999
Filed:
Mar. 14, 1997
Mansoor M Amiji, Attleboro, MA (US);
Northeastern University, Boston, MA (US);
Abstract
Drug-delivery devices and methods of their use are disclosed, which devices consist of at least a semi-interpenetrating network (semi-IPN) hydrogel comprising a first, cationic polymer such as chitosan and a second high molecular weight neutral polymer such as polyethylene oxide, the semi-IPN having been freeze-dried after formation of the semi-IPN, and a drug composition. A therapeutic method of treating gastric disease is also disclosed comprising the step(s) of introducing to a gastric area to be treated a drug-delivery device according to the disclosure, whereupon the device releases the drug or therapeutic agent contained in the device. The hydrogels of the disclosure are advantageously used for site-specific drug delivery in the gastro-intestinal tract where there is a range of pH from 1.0 to 1.5 in the stomach to about 7.5 in the small intestine.