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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 5902599 B1

PDFFull Text
Date of Patent:
May. 11, 1999

Filed:

Feb. 20, 1996

Biodegradable polymer networks for use in orthopedic and dental

Applicant:
Inventors:

Kristi S Anseth, Boston, MA (US);

Robert Langer, Newton, MA (US);

Venkatram R Shastri, Allston, MA (US);

Assignee:

Massachusetts Institute of Technology, Cambridge, MA (US);

Attorney:

Arnall Golden & Gregory, LLP

Primary Examiner:

Lynette F Smith

Assistant Examiner:

M K Zeman

Int. Cl.
CPC ...
A61F / ;
U.S. Cl.
CPC ...
424426 ; 424422 ; 424427 ; 424428 ; 424484 ; 424486 ; 424487 ; 5147726 ; 522-1 ; 522-6 ; 522 33 ; 522 38 ; 522 40 ; 522 43 ; 522 60 ; 523114 ;
Abstract

Biodegradable polymer networks are provided which are useful in a variety of dental and orthopedic applications. The biodegradable polymer networks can be formed in one embodiment by polymerizing anhydride prepolymers including crosslinkable groups, such as unsaturated moieties. The anhydride prepolymers can be crosslinked, for example in a photopolymerization reaction by irradiation of the prepolymer with light in the presence of a free radical initiator. Suitable anhydride prepolymers include dianhydrides of a dicarboxylic acid and a carboxylic acid molecule comprising a crosslinkable group. For example, methacrylic acid dianhydrides of monomers or oligomers of a diacid such as sebacic acid or 1,3-bis(p-carboxyphenoxy)-hexane can be used. The anhydride prepolymers can be applied in vivo to a site where an orthopedic implant is needed, and then may be crosslinked, for example, by irradiation with U.V. light, to form a biodegradable implant such as a rods, pin or plate. The implants advantageously provide mechanical support and also are capable of slow surface degradation to permit bone ingrowth.

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Anseth, Kristi. (1999). Biodegradable polymer networks for use in orthopedic and dental (U.S. Patent No. 5902599). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/5902599

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