The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 1999

Filed:

Jun. 04, 1997
Applicant:
Inventors:

Joseph Matthew Colacino, Indianapolis, IN (US);

Beverly Ann Heinz, Bargersville, IN (US);

Louis Nickolaus Jungheim, Indianapolis, IN (US);

Shawn Christopher Miller, Indianapolis, IN (US);

Wayne Alfred Spitzer, Indianapolis, IN (US);

Joseph Chiou-chung Tang, Carmel, IN (US);

Mark Joseph Tebbe, Indianapolis, IN (US);

Frantz Victor, Indianapolis, IN (US);

Assignee:

Eli Lilly and Company, Indianapolis, IN (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
5142345 ; 5142268 ; 514322 ; 514369 ; 514370 ; 514394 ; 544 55 ; 544139 ; 546199 ; 548181 ; 5483061 ; 5483074 ; 5483101 ;
Abstract

A series of benzimidazole compounds having the following general structure are provided which inhibit the growth of picornaviruses (e.g., rhinoviruses, enteroviruses, polioviruses, coxsackieviruses of the A and B groups, echo virus and Mengo virus) and flaviviruses (e.g., hepatitis C and bovine diarrheal virus). ##STR1## A method for inhibiting picornaviruses and flaviviruses is also provided which includes administering to a host an effective amount of the inventive benzimidazole compounds.


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