The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 1999
Filed:
Nov. 03, 1995
Yung Bok Han, Seoul, KR;
Hong Ki Kyung, Sungnam, KR;
Chun Won Kim, Seoul, KR;
E Tay Ahn, Seoul, KR;
Jong Bae Kim, Pohang, KR;
Hyo Suk Lee, Seoul, KR;
Kyung Yung Lee, Seoul, KR;
Eun Kyung Hong, Kunpo, KR;
Hee Sook Choi, Seoul, KR;
Sang Geon Kim, Seoul, KR;
Bo Im Yoo, Seoul, KR;
Hae Kyung Kwon, Seoul, KR;
Other;
Tae Rim Pharm. Co., Ltd., Kyungki-do, KR;
Abstract
The present invention relates to an anti-cancer composition containing acridine derivatives and guanosine compounds. In the composition of the present invention, the acridine derivative and the guanosine compound are present in the weight ratio of 1:0.1-5.0, preferably 1:0.3-3.0 and more preferably 1:0.5-1.5. In the composition of the present invention, most preferably the acridine derivative is acriflavine neutral and the guanosine compound is guanosine hydrate. Although acridine derivatives and guanosine compounds used as an active ingredient in the present composition have substantially no anti-cancer effect when they are used individually, the combination of acriflavine neutral and guanosine hydrate which potentiates the effect of acriflavine neutral, i.e. the composition(AG60) according to the present invention, exhibits reduced toxicity and increased anti-cancer effect in comparison to the use of acriflavine neutral or guanosine hydrate alone.