The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 06, 1999

Filed:

Nov. 07, 1997
Applicant:
Inventors:

Gary Arthur Amstutz, San Jose, CA (US);

Stephen Scott Bowersox, Menlo Park, CA (US);

Kishorchandra Gohil, Richmond, CA (US);

Peter Isadore Adriaenssens, Mountain View, CA (US);

Ramasharma Kristipati, Fremont, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K / ; A61K / ; C07K / ; C07K / ;
U.S. Cl.
CPC ...
514 12 ; 530300 ; 530324 ;
Abstract

A method of preventing progression of neuropathic pain is disclosed. The method includes administering to a subject an N-type voltage-sensitive calcium channel blocking compound which is characterized by its ability to (a) inhibit electrically stimulated contraction of the guinea pig ileum, and (b) bind selectively to omega conopeptide MVIIA binding sites present in neuronal tissue. Also disclosed are formulations effective to stabilize omega conotoxin peptide preparations at elevated temperatures. Novel omega conopeptides also form part of the invention.


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