The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 06, 1999
Filed:
Jul. 14, 1997
Applicant:
Inventors:
Daniel Schlieper, Koln, DE;
Harlad Sobek, Penzberg, DE;
Manfred Schmidt, Penzberg, DE;
Brigitte von Wilcken-Bergmann, Koln, DE;
Benno Muller-Hill, Koln, DE;
Assignee:
Boehringer Mannheim GmbH, Mannheim, DE;
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12P / ;
U.S. Cl.
CPC ...
9351723 ; 435 914 ; 435 9141 ; 4352523 ; 43525233 ; 4353201 ; 536 231 ; 536 241 ; 536 242 ;
Abstract
A vector according to the invention with a positive selection possibility for cloning a DNA sequence into a host cell transformed with the vector, wherein the vector contains suitable restriction cleavage sites within a selection gene the functional expression of which is prevented by insertion of the foreign gene is characterized in that it contains a modified cap gene as the selection gene which codes for a CAP protein with modified DNA binding specificity the expression of which is lethal for adenylate-cyclase-positive host cells.